Abstract
Background and Aims : During angiogenesis, endothelial cells form protrusive sprouts and migrate towards the angiogenic stimulus. Protrudin/ZFYVE27, an endoplasmic reticulum (ER)-anchored protein, is essential for neurite outgrowth. It also promotes invadopodia formation and invasion of breast cancer cells. However, the role of Protrudin in endothelial cell function is not known. In the present study we investigate the role of Protrudin in endothelial cell migration and angiogenesis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have