Role of pressure and wall shear stress in initiation and development of cerebral aneurysms

Abstract

Cerebral aneurysm is a cerebrovascular disorder in which weakness in the wall of a cerebral artery or vein causes a localized dilation or ballooning of the blood vessel. Other studies demonstrated that hemodynamic plays important role in the initiation and development of cerebral aneurysm. Wall shear stress and pressure are among the hemodynamic factors that contribute to the initiation and development of the cerebral aneurysm. In this study, the distribution of wall shear stress and pressure around cerebral aneurysms and its pre-aneurysms state were analyzed using the method of computational fluid dynamics.