Abstract
Objective To investigate the role of preoperative peripheral blood neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), prognostic nutritional index (PNI) in the prognosis of patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) after radical operation. Methods This is a retrospective study , involving 426 surgically resected hepatitis B related hepatocellular carcinoma cases in a single center from 2003 to 2012. Results Kaplan-Meier analysis showed patients in NLR ≤ 1.62 group achieve higher rate of recurrence-free and overall survival than that in the NLR >1.62 group, the difference was statistically significant (P 49.42 group showed higher rate of overall survival significantly than PNI≤49.42 group (P 1.62 (HR 1.74, P=0.007) and PNI≤49.42 (HR 0.70, P=0.021) were independent risk factors for overall survival, NLR>1.62 (HR 1.45, P=0.03) was also an independent risk factor for recurrence -free survival. Conclusion The preoperative NLR and PNI may be independent risk factors for prognosis of patients with HBV-related HCC after radical operation. Key words: Carcinoma, hepatocellular; Granulocytes; Lymphocyte; Nutritional assessment
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
