Abstract
Objective: Study the accuracy of 18F-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) scan in diagnosis of primary and loco regional recurrent breast masses compared with histopathological results and to correlate the results of 18F-fluoro-2-deoxy-D- glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) with histopathological findings in breast carcinoma patients. Methodology: This study is a prospective study conducted on 24 female patients presented to Ain Shams University Hospitals (oncology,surgery and obstetrics and gynecology departments) with pathologically proven breast cancer underwent PET/CT. Result: SUVmax of the tumor is directly related to the histopathological grade and to the size of the tumor. Invasive ductal carcinoma has predominantly higher SUVmax than invasive lobular carcinomas. Also SUVmax tumor/ SUVaverage liver is more accurate that SUVmax tumor alone. However, no relation between SUVmax and the presence of distant metastasis. 18F-FDG uptake may serve as a prognostic indicator for biological behavior in breast tumors
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