Abstract

Radiotherapy is commonly used to treat cancer patients. Besides the curable effect, radiotherapy also could relieve the pain of cancer patients. However, cancer pain is gradually alleviated about two weeks after radiotherapy. In addition, cancer patients who receive radiotherapy may also suffer from pain flare or radiotherapy-induced side effects such as radiation esophagitis, enteritis, and mucositis. Pain control is reported to be inadequate during the whole course of radiotherapy (before, during, and after radiotherapy), and quality of life is seriously affected. Hence, radiotherapy is suggested to be combined with analgesic drugs in clinical guidelines. Previous studies have shown that radiotherapy combined with oxycodone hydrochloride can effectively alleviate cancer pain. In this review, we firstly presented the necessity of analgesia during the whole course of radiotherapy. We also sketched the role of oxycodone hydrochloride in radiotherapy of bone metastases and radiotherapy-induced oral mucositis. Finally, we concluded that oxycodone hydrochloride shows good efficacy and tolerance and could be used for pain management before, during, and after radiotherapy.

Highlights

  • Radiotherapy is used as a curative or coadjuvant treatment for malignant tumors and plays an important role in the treatment of cancer. 60%∼70% of patients with cancer require radiotherapy in the clinic

  • Previous studies have shown that radiotherapy combined with oxycodone hydrochloride can effectively alleviate cancer pain to improve treatment compliance and quality of life for cancer patients. is paper analyzed the status of pain control during radiotherapy and attempted to evaluate the role of oxycodone hydrochloride in the management of the pain during the whole course of radiotherapy

  • Studies have shown that pain management is still inadequate for patients undergoing radiotherapy. e reason may arise from cancer pain in the waiting periods but overlooked the slow effect of radiotherapy on improving pain relief, and the radiotherapy-related complications

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Summary

Introduction

Radiotherapy is used as a curative or coadjuvant treatment for malignant tumors and plays an important role in the treatment of cancer. 60%∼70% of patients with cancer require radiotherapy in the clinic. 60%∼70% of patients with cancer require radiotherapy in the clinic. Previous studies showed that radiotherapy alone or combined with other treatment provides beneficial effect in cancer treatment for curative and palliative purposes [1]. It is reported that pain control is inadequate during the whole course of radiotherapy, and quality of life is seriously affected. It is stated in certain clinical guidelines that radiotherapy should be combined with analgesic drugs. Previous studies have shown that radiotherapy combined with oxycodone hydrochloride can effectively alleviate cancer pain to improve treatment compliance and quality of life for cancer patients. Previous studies have shown that radiotherapy combined with oxycodone hydrochloride can effectively alleviate cancer pain to improve treatment compliance and quality of life for cancer patients. is paper analyzed the status of pain control during radiotherapy and attempted to evaluate the role of oxycodone hydrochloride in the management of the pain during the whole course of radiotherapy

Necessity of Analgesia during the Whole Course of Radiotherapy
Role of Oxycodone Hydrochloride ProlongedRelease Tablets in Radiotherapy
Findings
Discussion
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