Role of ovarian markers in predicting pregnancy rates in infertile patients undergoing ICSI cycle

Abstract

Background Prediction of ovarian reserve has long been the golden key of reproductive endocrinology. Various endocrine [follicle stimulating hormone (FSH), inhibin B, estradiol (E2) etc.], and ultrasound tests [ovarian volume, antral follicle counts (AFC)] have been suggested to improve prediction of oocyte yield and pregnancy outcome following assisted reproductive technologies (ART).Purpose to investigate whether serum anti-mullerian hormone (AMH), follicle stimulating hormone (FSH), or antral follicle count (AFC) carry a predictive role for clinical pregnancy in intracytoplasmic sperm injection (ICSI) patients. Methods Serum AMH, FSH and AFC of 100 women under 40 years of age were investigated in this study. Pregnant and non-pregnant women were compared.Results 33 (33%) chemical pregnancies were observed in 100 women. Clinical pregnancy was found in 21 women (63.6%) of chemical pregnancy. Conclusion we concluded that Serum AMH was proved to be the most effective predictor in this study. Serum FSH wasn’t significant for both poor& high response groups. AFC was very helpful& cheap method for prediction.