Role of Oncogenic Viruses in Oral Squamous Cell Carcinoma

Abstract

Oral Squamous cell carcinoma (OSCC) is the most common oral malignancy which consistently ranks as one of the sixth most common cancer with significant morbidity and mortality. Oncogenic viruses, particularly Human Papilloma Virus (HPV) and Herpes simplex Virus (HSV) play an important role in the pathogenesis of OSCC. These viruses promote cell transformation and prompt uncontrollable cell generation, resulting in the formation of malignant tumors. The role of oncogenic viruses HPV, HSV in OSCC is presented.