Abstract
The study included 60 diabetic patients (30 patients type 2 diabetes mellitus complicated with diabetic retinopathy (DR) and 30 patients T2DM not complicated with DR). The study also included 30 healthy control individuals defended as subjects who apparently haven’t any chronic diseases. investigations were done including IL-6 and serum omentin-1. Fundus examination was carried out by an expert ophthalmologist. The study showed that the lowest mean of serum omentin-1 was recorded (P<0.05) in DR patients (687 pg/ml), and the highest (P<0.05)was in the control group (3540.625 pg/ml), The study also demonstrated that there was a significant decrease (P<0.05) in DM patients (991.2 pg/ml). The study also showed that serum IL-6 was increased significantly(P<0.05) in DR patients (253.7 pg/ml) as compared with the control group (35.33 pg/ml), The study also showed that serum IL-6 was increased significantly (P<0.05) in DM patients (102.5 pg/ml). The study showed negative correlation of serum omentin-1 concentrations with IL-6 in DR patients.
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