Abstract

Respiratory failure after a planned extubation is reported to be a common event, leading to reintubation. These reintubated patients have higher morbidity, mortality, hospitalization charges, and an increased length of hospital stay. The aim of this study was to assess the role of noninvasive ventilation (NIV) in decreasing the length of postextubation ICU stay. Fifty-six patients with respiratory failure type II were included in our study after exclusion of four patients who had self-extubation. Twenty-six patients were allocated to the NIV group and 26 to the control group. Physiological variables of the patients 1 h after the trial were mainly significantly better in the NIV group than in the standard medical treatment (SMT) group. Trial duration was significantly shorter in the NIV group than in the SMT group. This supports the use of NIV early after extubation in all patients regardless of risk for respiratory failure.

Highlights

  • Acute respiratory failure (ARF) in chronic obstructive pulmonary disease (COPD) generally marks a serious change in clinical state and is a frequent cause of admissions to the emergency and/or ICUs

  • Twenty-six patients were allocated to the Noninvasive ventilation (NIV) group and 26 to the control group

  • Trial duration was significantly shorter in the NIV group than in the standard medical treatment (SMT) group

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Summary

Introduction

Acute respiratory failure (ARF) in chronic obstructive pulmonary disease (COPD) generally marks a serious change in clinical state and is a frequent cause of admissions to the emergency and/or ICUs. Noninvasive ventilation (NIV) is a broad term for any ventilation therapy applied in a noninvasive manner – for example, through a mask, nasal prongs, or a helmet. This is in contrast to ‘invasive ventilation’, in which an endotracheal tube or a tracheal canula serves as an invasive interface between the patient and the ventilator. Respiratory failure after a planned extubation is reported to be a common event, leading to reintubation. These reintubated patients have higher morbidity, mortality, hospitalization charges, and an increased length of hospital stay

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