Abstract
Abstract: Most of the fundamental biological processes involve the interaction between various protein-coding and noncoding RNAs, and the RNA-binding proteins associated with them. The RNA-protein interactions results in the formation of ribonucleoprotein complexes (RNPs) and altercations in the levels and structure of either can affect the associated cellular function. Recent studies suggest that non-protein coding share of the genome is aggressively involved in multiple functions, ranging from gene expression, chromatin modification, to cell proliferation and involved in a wide range of diseases. Further studies on the mechanisms by which ncRNAs operate would yield a wealth of information regarding their functional role and the growing understanding of RNA biology to develop new RNA-based tools for developing therapeutics.
Highlights
Beena M KadakkuzhaMost of the fundamental biological processes involve specific interaction between Ribonucleic acids (RNA) molecules, both protein-coding and noncoding RNAs, and proteins
Ribonucleic acids (RNA) were earlier considered as a lowly messenger molecule that carries genetic information coded in the deoxy-ribonucleic acid (DNA) to the proteins
Once it was discovered that RNA could both carry information as well as catalyze chemical reactions, RNA occupied center stage leading to the "RNA world" hypothesis
Summary
Most of the fundamental biological processes involve specific interaction between RNA molecules, both protein-coding and noncoding RNAs, and proteins. The RNA-protein interactions results in the formation of ribonucleoprotein complexes (RNPs) and altercations in the levels and structure of either can affect the associated cellular function. Recent studies suggest that non-protein coding share of the genome is aggressively involved in multiple functions, such as gene expression, chromatin modification, cell proliferation and in a wide range of diseases. Further studies on the mechanisms by which ncRNAs operate would yield a wealth of information regarding their functional roles and the growing understanding of RNA biology to develop new RNA-based tools for developing therapeutics. To cite this article: Beena M Kadakkuzha.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
