Abstract
Disseminated carcinoma of the breast may affect the nervous system in a number of ways. Early recognition of neurologic symptoms caused by intracranial and intraspinal metastases will lead to rapid diagnosis, wherein lies the best hope of restoration of function by neurosurgical intervention. The judicious application of newer techniques for the relief of pain has improved the quality of survival for patients with advanced cancer. Pituitary ablation has a definite role in the sequential management of patients with disseminated cancer of the breast, and, because if its low morbidity and freedom from serious complication, stereotaxic cryohypophysectomy can be recommended for postmenopausal patients after initial trials of hormonal therapy.
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