Abstract
Longitudinal studies using neuropsychological tests have reported that cognitive changes may be observed up to 20 years before diagnosis of dementia. These findings suggest that neuropsychological tests may serve as potential screening tools during the preclinical phase of Alzheimer's disease. However, routine cognitive screening tests show limited sensitivity for prediction of dementia. Therefore, careful selection of appropriate neuropsychological tests is essential for effective screening of dementia during the preclinical stages.
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