Abstract
Neuropeptides are proteins generated from somatosensory and autonomic nerve fibers after tissue injury. Neuropeptides play an important role in hemodynamic changes and pain mechanisms in the pulp. Neuropeptides also play an active role in orthodontic tooth resorption, restorative procedures involving carious dentin and acid etching. They are responsible for difficult anaesthesia in inflamed teeth. This paper highlights the role of neuropeptides seen in the dental pulp.
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