Abstract

There are various complexities involves with enzymatic glucose sensors such as poor shelf life due to the inherent instability of an enzyme, a fabrication complexity included in enzyme immobilization procedures and interference caused by soluble redox mediators. Therefore, research towards enzymeless glucose sensing has increased. Further, the integration of photovoltaic or alternate energy harvesting methods with glucose sensors results in the development of cost-effective and energy-efficient biosensor systems. Continuous technological advancements of novel materials having distinctive nanostructures assist in understanding the fundamentals of enzymeless glucose detection. In this paper, we have discussed the electrochemical method of glucose detection and the role of nanostructures in development of energy-efficient electrochemical non-enzymatic glucose sensors.

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