Role of Nanomedicine in Management and Prevention of COVID-19

Jitendra N Wankar,Mohan P Singh,Vivek K Chaturvedi,Raghvendra A Bohara,Chandrashekhar Bohara

doi:10.3389/fnano.2020.589541

Abstract

COVID-19, or the Coronavirus disease 2019, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a pandemic. At the time of writing this (July 28, 2020), more than 17 million people have become affected and 0.7 million people have died across the world. Remdesivir has shown glimpses of insight into how to fight the virus, but as of yet remain far from victory. Nanotechnology has proven its role in medicine to deliver the drug at the target site with minimal side effects, particularly in the anticancer domain. Most specifically, a range of nanotechnology-based products, such as nanosilver, are currently on the market because they have demonstrated the potential to combat viruses. This article provides an overview of the role of nanomedicine, including polymeric and inorganic materials, and its future capabilities in the management of the disease outbreak. Taking all this into account, an attempt has been made to educate readers in the simplest way of the role of nanomedicine, which can play a pivotal role in the management of diseases.

Highlights

The disastrous outbreak of COVID-19 originated in China, and its Wuhan province was the first epicenter of this pandemic (Wu et al, 2020)
COVID-19 is a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused by a novel coronavirus that has encountered humans for first time, and as a result humans lack the innate immunity to fight against this novel strain of the coronavirus which results in severe miscommunication among health care facilities (Al-Qahtani, 2020; Wu et al, 2020)
Due to the pandemic situation, it was difficult to handle the enormous amounts of patients who required treatment, which placed a burden on the healthcare industry, and the death rate was higher than expected

Summary

INTRODUCTION

The disastrous outbreak of COVID-19 originated in China, and its Wuhan province was the first epicenter of this pandemic (Wu et al, 2020). It reduces the high dose-related side effects and permeability across the cellular membrane due to its nano-size properties This beneficial effect of the polymeric nanoparticle can be utilized for drug delivery to revive the existing drug to treat the SARS-CoV-2 infection. This artificial cellular nanosponge acts as a receiving target for SARSCoV-2 during incubation where it becomes neutralized and unable to infect the host cells (Kumari et al, 2018) In this way, the polymeric nanoparticle is a potential nanocarrier system to deliver drugs to treat SARS-CoV-2 infection.

Composites with silver Inhibited the growth Transmissible gastroenteritis

CONCLUSION