Abstract

Background and Aims : NAFLD is associated with an increased risk of chronic kidney disease (CKD). Also, recent observations focused the attention on the role of PNPLA3 rs738409 variant in the relationship between NAFLD and CKD in non-metabolic patients, but the genetic impact on this association is still matter of debate. We aim to investigate the potential influence of PNPLA3, TM6SF2, MBOAT7 and GCKR gene variants on renal function in a large population of NAFLD patients.

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