Abstract
Calcium signals evoked at depolarization of the cell membrane and their modifications induced by blocking of accumulation of these ions in the mitochondria and blocking of mitochondrial Na+/Ca2+ exchange were studied in dorsal root ganglion neurons of mice with the use of fluorescent measurements of shifts in the intracellular Ca2+ level. Mitochondria aredemonstrated to be actively involved in formation of these signals by rapid peak absorption of Ca ions from and their subsequent return to the cytosol.
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