Abstract
Magnesium, the second most prevalent intracellular cation, is important for the activation of many enzymes which are necassary in providing energy for transport and in regulating various processes in the cell and the cell membrane. Magnesium induces changes in calcium permeability, exchange in vascular smooth muscle, and influences synthesis and secretion of vasoactive substances (Altura and Altura 1981). Evidence is beginning to mount indicating that magnesium is important in blood pressure regulation and that it may be involved in the pathogenesis of hypertension. In this paper, the results of experiments performed in various animals regarding the possible role of magnesium in blood pressure regulation will be reviewed.
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