Role of IVUS, OCT and FFR in peripheral vascular intervention

Abstract

COPD is a chronic progressive and inflammatory respiratory disease. Close, complex & bidirectional association of cardiovascular morbidity exists with COPD. There is growing evidence that LV function is also commonly impaired in COPD patients, more so with diastolic dysfunction (LVDD) than systolic (LVSD). The present study is a cross-sectional observational study conducted in a tertiary care medical college hospital in Kerala to understand the prevalence of LV dysfunction, systolic and diastolic in COPD patients and their association with the 8 traditional risk factors- age, smoking, sex, hypertension, diabetes mellitus, coronary artery disease(CAD), dyslipidemia, thyroid disease. Our study found significant LVDD in 45% patients, and a significant association of thyroid disease with COPD and LVDD. The prevalence of LVSD was 24%, significant when COPD is associated with CAD, hypertension and dyslipidemia independently. This study emphasizes the need to consider possibility of LV dysfunction in COPD patients, along with the traditional risk of right heart failure. The assessment and treatment modalities of COPD patients with LV dysfunction needs to be revised, since they are at increased risk of pulmonary edema and mortality.