Role of innate lymphoid cells in the pathogenesis of respiratory virus-induced asthma

Abstract

Asthma is a chronic airway inflammatory disease caused by a variety of factors.Viral infection (especially respiratory syncytial virus) induced bronchiolitis in infancy has become one of the most important factors in the pathogenesis of asthma after childhood, and the acute exacerbation of asthma in adulthood is also related to viral infection.The relationship between respiratory virus infection and asthma and its pathogenesis are still not clear.Recent studies have found that innate lymphoid cells may play an important role in regulating the immune response of respiratory virus infection and asthma, the progress in this field is to be reviewed in the article. Key words: Innate lymphoid cells; Viral infections; Respiratory syncytial virus; Rhinovirus; Asthma; Immune tolerance