Abstract
Background: For patients undergoing surgery for peritrochanteric fractures, blood loss is a big issue. The purpose of this study was to see if tranexamic acid (TXA) could reduce postoperative blood loss in individuals who had hip surgery for peritrochanteric fracture. Methods: A total of 69 patients with intertrochanteric fractures were enrolled in this prospective study. Patients are randomly divided into two groups. Group A patients received 200 mL (1 g) of TXA intravenously before peritrochanter surgery and Group B patients did not receive an injection of TXA. Haemoglobin and hematocrit values were measured preoperatively and postoperatively at days 1 and 3. Visible and hidden blood loss volumes were calculated on postoperative day 3. Results: The blood transfusion rate was reduced significantly in patients by injecting tranexamic acid before surgery. However, mean haemoglobin and hematocrit levels were not significantly different between patients who received injection tranexamic acid and those who did not receive injection tranexamic acid. Conclusion: TXA significantly reduced postoperative blood loss in patients with Peritrochanteric fractures who underwent surgery.
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