Role of hypothermia in the immediate postoperative period on mortality in a surgical ICU

Ar Santana,L De Jesus Almeida,App Amorim,Gm De Andrade Filho,Ta Rodrigues,Ta Silva,Lc De Carvalho Santos,Lg De Souza Godoy,Ja De Araújo Neto,M De Oliveira Maia,Fb Soares,Ff Amorim,Eb De Moura,Pn Ferreira,Mpb De Araújo

doi:10.1186/cc12675

Abstract

Surgical patients are submitted to numerous factors that may cause postoperative hypothermia, such as a cool operating room environment, cold intravenous fluids and blood, cold antiseptic skin preparations and anesthetic-induced impairment of thermoregulatory control. Hypothermia may increase susceptibility to surgical wound infection, length of stay, intraoperative blood loss, morbid cardiac events, postoperative shivering, coagulopathy and also altered duration of drug action. The objective of this study was to evaluate the impact of hypothermia at ICU admission on hospital length of stay and mortality in a surgical ICU.

Highlights

Vascular calcification is a regulated process, which associates with coronary artery disease (CAD) and occurs through an increase in transcription factor expression such as RUNX2, MSX2 and alkaline phosphatase (ALP), inducing calcium deposition
The objective of this study was to verify the incidence of delirium through the CAM ICU instrument in ICU patients followed by physiotherapists
There was a low incidence of delirium in ICU patients followed by physiotherapists

Summary

Introduction

Vascular calcification is a regulated process, which associates with coronary artery disease (CAD) and occurs through an increase in transcription factor expression such as RUNX2, MSX2 and alkaline phosphatase (ALP), inducing calcium deposition. The objective of this study was to evaluate the tendency of the plasma concentration and clearance of PCT as biomarkers for prognosis of patients with severe sepsis and septic shock, compared with another early prognosis marker, the number of SIRS criteria at sepsis diagnosis. The objective of this study was to evaluate the serum activity of MMP-2 and MMP-9, length of hospital stay, length of ICU stay and mortality in patients with septic shock. The objective of this study was to determine the influence of serum thiamine concentrations on lactate levels, GPx activity, length of hospital stay, length of ICU stay and ICU mortality in patients with septic shock. Hypothermia at ICU admission was associated with greater severity scores and increased hospital mortality in this sample of surgical patients studied.

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Conclusion