Abstract
One of the chief functions of hyaluronic acid (HUA) and soluble protein~chrondroitinkeratan,sulfate (PCKS) in the animal organism is to restrict dispersion and concentration of cells, their organelles, and certain other tissue components in the necessary volume [3, 5, 8, 11-14]. Investigations using suspensions of rabbit red cells in saline as the model of isolated cells have shown that heparin (the total preparation) and its two individual fractions, one of which contains three (HP-3) the other four (HP-4) sulfate groups for each re. peated dissacharide unit of the macromolecules, weaken or totally suppress this action of HUA and PCKS in a concentration of I0 mg.ml-* [3].
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