Role of hematopoietic growth factor in the treatment of acute radiation injury

Abstract

Acute radiation damage caused by nuclear wars or nuclear power plant accidents is one of the major diseases that seriously threaten human health. Therefore, the development and application of radioprotectants have become the primary task in dealing with radiation threats. Hematopoietic growth factor plays an important role in inducing and promoting the proliferation and differentiation of hematopoietic cells. It is an effective strategy for the treatment of acute radiation syndrome. In recent years, the application of hematopoietic growth factor in the treatment of acute radiation injury has achieved satisfactory clinical efficacy and accumulated rich experience. However, the research on the treatment mechanism of acute radiation damage, the timing of the drug, the dose and the reasonable compatibility need to be further discussed and summarized. This paper reviews the current status and progress of this research. Key words: Hematopoietic growth factor; Acute radiation injury; Treatment