Abstract

AIM: Study to evulate the pattern of the hematolofical parameters of covid-19 patients along with their clinical course in the Indian scenario.
 Material& method: A prospective study of 100 patients with laboratory-confirmed covid-19 admitted to index medical college indore from April to june were enrolled for the study. Patients were divided into asymptomatic (mild) patients, and symptomatic (moderate).
 The demographic date, the clinical status of the patients during admission, and follow up and hematological finding were recorded. The semples for complete blood count and peripheral smears for microscopy examination were collected on the day of admission .the sample were tested for complete blood count on 5-part hematology analyzer, and values were recorded. peripheral smears were stained by gimsa stains, and findings were noted.
 Results: All the paediatric cases under study were stable and asymptomatic, with only supportive treatment. Adults patients included in the study were given supportive treatment, and only one case showed clinical deteriotion over a period of 90 day of admission.
 Conclusion: The study of 100 covid-19 cases of Indian population shows that majority of the patients are younger, have asymptomatic to mild clinical presentation, and a higher incidence in the female population. The majority of pediatric cases have mild symptomology with a stable clinical corse. Baseline CBC finding of all the cases show. mild neutrophilia, mild lymphopenia, eosinophilia, mild monocytosis, and a normal to mild thromobocytopenia. a significance statistical trend of increase in CBC PARAMETER, NLR, was noted in follow up cases with persistent symptoms, however, a larger follow up cohort is needed to arrive at a statistical significances.
 Keywords: hematological, covid-19 & neutrophilia.

Highlights

  • The Virus is spreading around the World, assuming the dramatic features of a pandamic emergency

  • The semples for complete blood count and peripheral smears for microscopy examination were collected on the day of admission .the sample were tested for complete blood count on 5-part hematology analyzer, and values were recorded. peripheral smears were stained by gimsa stains, and findings were noted

  • The study of 100 covid-19 cases of Indian population shows that majority of the patients are younger, have asymptomatic to mild clinical presentation, and a higher incidence in the female population

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Summary

Introduction

The Virus is spreading around the World, assuming the dramatic features of a pandamic emergency. On the 11th March 2020, WHO declared the COVID-19 as a pandemic[1]. India confirmed its first case on 30TH January 2020 in Kerala. The clinical characterization of COVID-19 has been broadly by WHO with most of the confirmed COVID-19 Cases have mild to moderate clinical presentation. Considering the high infectivity and mortality rates of COVID-19, early diagnosis of the disease is essential. The definitive diagnosis of this disease is made by proving a viral presence in real-time PCR analyses. Due to factors such as the high number of samples, limited number of staff trained in performing the aforementioned tests and insufficient lab capacities, the time it takes to receive results can be prolonged[4]. The possibility of diagnosing COVID-19 early in ER visits by a simple, inexpensive, accessible test, such as a CBC, has been examined[5]

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