Abstract
Glutamate is a major mediator of excitatory signals in the nervous system and is involved in many physiologic and pathologic processes. The understanding of glutamatergic transmission in the nervous system has been greatly expanded and the family of ionotropic and metatropic glutamate receptors. The glutamate receptors are localized at nerve terminals postsynaptic sites and glial cells and thus, they can influence and modulate the action of glutamate at different levels in the synapse. Moreover, there is substantial evidence of glial participation in glutamate nociceptive processes and neuropathic pain. Present study explains the glutamate transporters are responsible for the level of glutamate in the synaptic cleft is principally dependent on neuronal glutamate transporters in rat model.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Indian Journal of Public Health Research & Development
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
