Abstract
Background: Mercurial preparations known by the name of Kupipakwa Rasayana are prepared in a glass bottle by adopting gradual temperature gradient. Aims and Objectives: To elucidate the jarana process (role of temperature and time) process in kuipakwa rasayan. Materials and Methods: Two sample of Malla Sindura was prepared by heating a mixture of Parada (mercury), Gandhaka (sulfur), and Malla (arsenic) in a Kupi (glass bottle covered with mud smeared cloth) placed in an electric muffle furnace at two different temperature and time duration ie 24 and 48 hrs. Final product deposited at the neck of bottle was collected as Malla Sindura. Results and Conclusion: Three batches of each sample of Malla Sindura was prepared by adopting gradient temperature pattern for 24 hrs and 48 hrs i.e., 8 h of mild (120-250°C), moderate (250-450°C) and strong heating (450-600°C) for SDMS and 18 hrs of mild (140-250°C), 22 hrs moderate (250-450°C) and 8 hrs strong heating (450-630°C) for LDMS each. Average yield of Malla Sindura in two samples is 151.33 g (37.83%) and 237.7 g (59.42%) using 400 g Kajjali in each batch respectively.
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