Abstract
Antigens of the Campylobacter jejuni heat-labile serotyping system developed by Lior were analysed by immunoblotting. The essential component of C. jejuni strains recognized in serogroups 5, 6, 7 and 16 was the 62,000 Da (62 kDa) molecular weight flagellar protein and loss of flagella resulted in the untypability of these strains in the homologous absorbed antisera. In contrast, an unflagellated derivative of a serogroup 38 strain maintained its serogroup specificity in the corresponding-absorbed antiserum. Immunoblots of C. jejuni serotype 38 strains demonstrated weak recognition of three other proteins (45, 38 and 31 kDa) in both flagellate and aflagellate derivatives. A minor component was attributed to the flagellum which was present only in the flagellated derivative. Although for several serogroups, the main component of the heat-labile serotyping system was the flagellum, other somatic antigens appeared to play a role in recognition of at least one serogroup.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Serodiagnosis and Immunotherapy in Infectious Disease
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
