Abstract
Studies were undertaken to demonstrate the role of fetal antigens in tumor immunity. Viable fetal cells inoculation followed by challenge with transplanted methylcholanthrene induced tumor cells after 7, 14 and 21 days significantly delayed the time of appearance of tumors. Transfer of lymphoid cells from mice immunized with fetal cells followed by tumor challenge resulted in delayed appearance of tumors. Inoculation of viable tumor cells pre-treated in vitro with serum from mice immunized with fetal cells shortened the time of appearance of tumors in mice.
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