Abstract
To evaluate diagnostic yield and the safety of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for mediastinal/hilar lymph nodes and intrapulmonary masses. Between July 2009 and February 2010, 95 patients with mediastinal/hilar lymphadenopathy and/or intrathoracic peritracheal or peribronchial masses detected with computed tomography underwent EBUS-TBNA. One hundred and twelve samples were obtained from lymph nodes (LNs) and 11 samples were obtained from intrapulmonary lesions. All patients had cytological evaluation by smears and/or tissue evaluation of aspiration specimens. Out of the 95 patients, 60 had lung cancer, 58 of these patients were diagnosed using EBUS-TBNA without onsite cytology assistance, false negative in 2 cases. Sensitivity the of convex probe EBUS-TBNA method in distinguishing benign from malignant lymph nodes or thoracic mass was 96.67%. In the absence of any major complications the procedure was uneventful. EBUS-TBNA seems a safe and effective technique in the diagnosis making bronchogenic carcinoma for mediastinal/hilar lymph nodes (LNs) and intrapulmonary masses.
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