Abstract
About more than half of the drugs currently in use are chiral compounds. Although few drugs were used as racemates, most of the drugs are founds as single enantiomer. With the same chemical structure, most of the enantiomers of chiral drugs exhibit marked differences in biological activities such as pharmacology, toxicology, pharmacokinetics, metabolism etc. In this review we comprised some of the notable chiral drugs, their mechanism of action and their structure activity relationship.
Highlights
Role of Chirality in DrugsSubmission: February 6, 2018; Published: February 23, 2018 *Corresponding author: Nallamuthu Ananthi, Department of Chemistry, Karunya Institute of Technology and Sciences, Coimbatore, Tamil Nadu, India, Tel: 99941 49762, Email: Abstract
Chirality has become a major role for the synthesis and development of drugs
This review outlines the basic concept of Chirality, the effect of Chirality on the efficiency of drugs and interesting potential chiral drug molecules
Summary
Submission: February 6, 2018; Published: February 23, 2018 *Corresponding author: Nallamuthu Ananthi, Department of Chemistry, Karunya Institute of Technology and Sciences, Coimbatore, Tamil Nadu, India, Tel: 99941 49762, Email: Abstract. About more than half of the drugs currently in use are chiral compounds. Few drugs were used as racemates, most of the drugs are founds as single enantiomer. With the same chemical structure, most of the enantiomers of chiral drugs exhibit marked differences in biological activities such as pharmacology, toxicology, pharmacokinetics, metabolism etc. In this review we comprised some of the notable chiral drugs, their mechanism of action and their structure activity relationship
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Organic & Medicinal Chemistry International Journal
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
