Role of carotid intima-Medical thickness in predicting ischemic stroke

Abstract

Background: Combined carotid intima-media thickness (CIMT) is a marker of atherosclerosis and is also a predictor for ischemic stroke. Objective: To determine CIMT and serum lipid levels in patients of ischemic stroke. Method: A total of 120 patients enrolled in this study 60 cases and 60 controls group. No history of ischemic stroke in control group. The age group was 40-50 years, 50-60 years and 60-70 years. A detailed history of cases and controls was taken, clinical examination and high-resolution Ultrasonography. They were subjected to routine investigations, blood sugars and lipid profile. Result: A total of 20% ischemic stroke patients and 33.3% of control patients found within age group of 40 to 50 years. In age group of 50 to 60 years 35% ischemic stroke patients and 26.7% in control groups. The age group of 60 to70 years included 45% ischemic stroke patients and in control group 40%. The ischemic stroke patients had experienced highly significant CIMT at right (0.723±0.070 millimeter) common carotid artery as compared to controls (0.501±0.061 millimeter) had no previous history of stroke. Conclusion: There is increase in CIMT in patients of ischemic stroke. Elevated serum lipid concentration is related to the occurrence of ischemic stroke in the elderly cohort, an association that is largely dependent on atherosclerosis severity as measured by CIMT.