Role of carboxyl ester lipase (CEL) in pancreatic disease: Functional characterization of CEL protein variants differing in C-terminal sequence

Abstract

An improved quantum-behaved particle swarm optimization (IQPSO) algorithm is employed to determine aerosol size distribution (ASD). The direct problem is solved using the anomalous diffraction approximation and Lambert–Beer's Law. Compared with the standard particle swarm optimization algorithm, the stochastic particle size optimization algorithm and the original QPSO, our IQPSO has faster convergence speed and higher accuracy within a smaller number of generations. Optimization parameters for the IQPSO were also evaluated; we recommend using four measurement wavelengths and 50 particles. Size distributions of various aerosol types were estimated using the IQPSO under dependent and independent models. Finally, experimental ASDs at different locations in Harbin were recovered using the IQPSO. All our results confirm that the IQPSO algorithm is an effective and reliable technique for estimating ASD.