ROLE OF BONE MARROW ASPIRATION AND MARROW BIOPSY IN HAEMATOLOGICAL DISORDERS

Abstract

Background: Bone marrow aspiration and bone marrow trephine biopsy are the two procedures done for the diagnosis of both hematological and non-hematological disorders and are complimentary to each other. To studyAim and Objective: the essential haematological evaluation of cases where bone marrow aspiration and bone marrow biopsy is indicated and to correlate the ndings of bone marrow aspiration and bone marrow biopsy in diagnosing various haematological disorders. The study wasMaterial and Methods: done on 86 patients in the age group 10-80 years. All had undergone simultaneous bone marrow aspiration and bone marrow biopsy procedures in the department of Clinical Haematology in a tertiary hospital. Standard methods were followed for bone marrow aspiration and biopsy procedure and for staining and evaluation of cellular aspirate. The Male to Female ratio of 1.4:1; 60% of patients belonged to 20-Observation & Results: 60years group. Bone marrow and aspiration yield high diagnostic evaluation in megaloblastic anaemia (89.47%) against aspirates (10.52%) with p value of 0.00086 while in aplastc anaemia the aspirate evaluation shows better diagnostic yield (p value of 0.285). A combinationConclusion: of bone marrow aspiration and bone marrow biopsy give a better morphology of the cells and with good picture of the architecture and pattern of distribution of the cells. There is high diagnostic yield in evaluation of anemia.