Abstract
The joint attack on the body by metabolic acidosis and oxidative stress suggests that treatment in degenerative diseases, including Alzheimer's disease (AD), may require a normalizing of extracellular and intracellular pH with simultaneous supplementation of an antioxidant combination cocktail at a sufficiently high dose. Evidence is also accumulating that combinations of antioxidants may be more effective, taking advantage of synergistic effects of appropriate antioxidants as well as a nutrient-rich diet to prevent and reverse AD. This review focuses on nutritional, nutraceutical and antioxidant treatments of AD, although they can also be used in other chronic degenerative and neurodegenerative diseases.
Highlights
Countless lives have been saved with antibiotics and vaccines for various communicable diseases [1,2]
In Europe, current estimates are that 50 million people live with multiple chronic conditions and this number is expected to increase during the decade [6]
Considering the multifactorial nature of Alzheimer’s disease (AD) and the factors discussed above it may suggest that AD, like other neurodegenerative diseases and likely all degenerative diseases, may have a common link
Summary
Countless lives have been saved with antibiotics and vaccines for various communicable diseases [1,2]. Roses has provided two excellent reviews on the economics and future of using pharmacogenetics to produce drugs with greater efficacy and safety on a more personalized treatment basis instead of limited efficacy for 30–40% of medicated patients [7,8]. It may take another 10 years or more for clinically trailed drugs to be brought to market. Medicinal drugs used to treat chronic illnesses need to be taken daily for the rest of each patient’s life [9] and are very profitable for the companies that produce them. We will focus on nutritional, nutraceutical and antioxidant treatments of AD, they can be used in other chronic degenerative and neurodegenerative diseases
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