Abstract
Posttraumatic seizures (PTS) have been recognized as a major complication of traumatic brain injury (TBI). The annual incidence of TBI in the United States is 1.7 million. The role of anticonvulsants in the treatment of posttraumatic epilepsy (PTE) remains uncertain. Based on current studies, however, anticonvulsants have been shown to reduce early PTS occurring within the first 7 days, but little to no benefits have been shown in late PTS occurring after 7 days. In this paper, we provide a mini review of the role of anticonvulsants and current advances in the management of PTE.
Highlights
We provide a mini review of the role of anticonvulsants and current advances in the management of posttraumatic epilepsy (PTE)
Limited scientific data exist, which are specific to PTE with other anticonvulsants, and there is a need for additional controlled randomized clinical trials to explore more options
The PTE can be differentiated from Posttraumatic seizures (PTS) that are sequelae from traumatic brain injury (TBI)
Summary
Kirmani1* , Diana Mungall Robinson , Ekokobe Fonkem , Kevin Graf 3 and Jason H. University of Florida, USA Elham Abbasloo, Kerman Physiology Research Center, Iran. Posttraumatic seizures (PTS) have been recognized as a major complication of traumatic brain injury (TBI). The annual incidence of TBI in the United States is 1.7 million. The role of anticonvulsants in the treatment of posttraumatic epilepsy (PTE) remains uncertain. Anticonvulsants have been shown to reduce early PTS occurring within the first 7 days, but little to no benefits have been shown in late PTS occurring after 7 days.
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