Abstract
Introduction : Anti-cardiolipin antibodies are autoantibodies which may be associated with unexplained recurrent abortions. Aims&Objectives : To evaluate the role of anti-cardiolipin antibodies in unexplained, recurrent abortions. Materials&Method : A cohort of 28 females with recurrent spontaneous abortions were studied for anti-cardiolipin antibodies by ELISA. 20 normal fertile age matched females served as controls. Result : 25% cohorts were positive for anti-cardiolipin antibodies. They also had increased frequency of the antibody (35%) as compared to primary aborters (12.5%). All healthy controls were negative. All positive cases were either moderately or weakly positive for the antibody by ELISA. Conclusion : Anti-cardiolipin antibodies may be associated with spontaneous recurrent abortion. It should be tested in all cases of recurrent miscarriages.
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