Abstract
Anaerobic bacteria comprise a major portion of the pathogenic bacteria in chronic sinus and ear infections, as well as the complications of these infections. Thus, therapy for frontal osteomyelitis, subdural abscess, orbital abscess, lateral sinus thrombosis, and brain abscess should include antibiotics that penetrate the central nervous system as well as cover anaerobic organisms. Penicillin, metronidazole, and chloramphenicol are three such agents.
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