Abstract
Changes in cellular metabolism are common properties observed in various cancers. However it remains poorly understood whether metabolic changes directly affect cancer development and progression. In chronic myelogenous leukemia (CML), disease can progress from an indolent chronic phase to an aggressive blast crisis phase in which cellular differentiation is arrested and extensive self-renewal of cancer cells occur. By studying mouse CML models, we identified an amino transferase that mediates CML disease progression.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
