Role of Adjuvant Therapy in Older People with Breast Cancer

Abstract

ABSTRACTThe expanding population of older people with breast cancer is challenging for the clinician. While a wealth of data on younger women assists doctors in the discussion of adjuvant therapeutic options, these are not necessarily applicable to older women. This issue is discussed in this article in relation to the efficacy and toxicity of adjuvant chemotherapy, hormone therapy and biological therapy in the older population. The differing stage and biology of breast cancer in the elderly is also highlighted. The development of using the Comprehensive Geriatric Assessment tool in the clinical assessment of older patients is also outlined.