Abstract
Galectin 3 (Gal-3) is a protein belonging to family lectins. Gal-3 is produced as a response to inflammatory mediators by several types of cells directly associated with atherosclerosis such as macrophages and endothelial cells. Galectin 3 represents a link between inflammation and fibrosis. Gal-3 is a biomarker associated with inflammation and cardiac fibrosis in patients with heart failure. Association of galectin 3 with cardiovascular risk factors suggest that it can be a promising marker of subclinical and symptomatic atherosclerosis. Previous research suggest that Gal-3 may be a useful diagnostics marker and prognostic factor in ischaemic heart disease and heart failure.
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