Abstract
Graphitic Carbon Nitride (g-CN) nanomaterials are emerging effective biomaterials and play a vital role in the biodiversity research area due to their biocompatibility, and less toxic nature. The nanosized g-CN rod-like nanosheets were synthesized and characterized with XRD, FTIR, UV–Vis and Fluorescence spectroscopy, FESEM, EDAX and HRTEM analysis. The g-CN appears almost immediately. DNA cleavage and anticancer activity investigations were conducted using Cu2+ ions. The size and Lewis acidic and Lewis basic functions of Cu2+/g-CN played a vital role in effective DNA cleavage and anticancer activity were demonstrated. The g-CN, Cu2+ ions, Cu2+/g-CN nanostructure and its various concentrations at different times were studied for the DNA cleavage and anticancer activity. The DNA interaction with Cu2+ ions/g-CN rod-like nanosheets was also established with UV–Vis and Fluorescence analysis. The Cu2+/g-CN nanostructure showed highly efficient activity than the other concentrations and controls were used in this study. The specificity and effectiveness of the present DNA slicing agent and anticancer nano-drug carrier system may value the investigation of cancer pharmaceutics.
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