Abstract

Achalasia is an esophageal motor disorder that is characterized by failure of the lower esophageal sphincter (LES) to relax and loss of peristalsis in the esophageal body.1 Treatment options focus on releasing the elevated pressure of the LES and include direct botulinum toxin injection, pneumatic dilation, per-oral endoscopic myotomy (POEM), and Heller myotomy. Botulinum toxin's effect is temporary, requiring repeated injections with progressively diminished efficacy over time. The effectiveness of pneumatic dilation has been shown in previous studies.

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