Abstract
SummaryInitial inhibition of label accumulation into RNA of rhinovirus infected cells occurs 5 hr postinfection when viral RNA synthesis is at a maximum. Infection lowers the level of label accumulation into protein with maximum inhibition occurring late in the cycle. Actinomycin D does not significantly affect protein synthesis in infected cells. These results support the hypothesis that two separate functions are responsible for inhibition of host RNA and protein synthesis.This investigation was supported by Research Contract NIH 69-2062 from the National Institute for Allergy and Infectious Diseases, and by U.S. Public Health Service General Research Support Grants 22-14-54 and 22-15-74 from the Children's Hospital Research Foundation. Miss Judy Halstead provided valuable technical assistance.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
