Abstract

Glaucoma is an eye disease that leads to irreversible vision loss. Accurate Optic Disc (OD) and Optic Cup (OC) segmentation can effectively facilitate ophthalmologist in glaucoma diagnosis. Recently, a series of deep learning approaches attain promising performance in OD and OC segmentation but still face the challenge to precisely segment OC boundary with enhanced computational efficiency. To address this issue, we propose a novel network named Robust Multiscale Feature Extraction with Depthwise Separable Convolution (RMSDSC-Net), which can better solve the challenging tradeoff between segmentation performance and network cost. The proposed RMSDSC-Net is mainly composed of Multiscale Input (MSI), Depthwise Separable Convolution Unit (DSCU), Dilated Convolution Block (DCB), and External Residual Connection (ERC). First, the introduction of MSI can reduce the information loss due to the pooling layers used in the network for capturing rich feature representations. Next, to enhance segmentation performance and computational efficiency, this paper designs DSCU and DCB modules to avoid spatial information loss from minor details of the image and preserve more high-level semantic features. Finally, this paper develops ERC established between the encoding layers and decoding layers to minimize the feature degradation problem. Hence, a high segmentation performance can be achieved using a shallow network. To evaluate the performance of the proposed network, extensive experiments have been enforced on two publicly available databases, DRISHTI-GS and REFUGE. Our approach outperforms the state-of-the-art approaches with the Dice Coefficient of (0.978, 0.919) and (0.965, 0.910) for OD and OC segmentation on DRISHTI-GS and REFUGE databases, respectively. As a result, the proposed approach has a strong potential in analyzing fundus images for glaucoma diagnosis.

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