Abstract
Most patients presenting to the emergency department for treatment of severe migraine headache receive parenteral analgesics or vasoactive agents. These researchers evaluated the efficacy of oral rizatriptan, a serotonin (5-HT1B/1D) receptor agonist that, in wafer form, dissolves in the mouth, absorbs rapidly, and easily crosses the blood-brain barrier. In this prospective, unblinded, observational, manufacturer-supported study, patients were excluded for …
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