Abstract
BackgroundA report of the second known case of bilateral cystoid macular edema in a patient taking risperidone.Case presentationWe report a case of a 69-year-old African American woman using risperidone who presented with worsening visual acuity and was found to have bilateral cystoid macular edema. Upon decreasing the dosage of risperidone, the cystoid macular edema resolved and visual acuity markedly improved. Fluorescein angiography and optical coherence tomography were used to document the severity of cystoid macular edema and subsequent resolution after decreased dosage of risperidone.ConclusionThe documentation of a patient who developed cystoid macular edema associated with risperidone usage indicates that it may be beneficial to monitor patients taking risperidone for the development of maculopathy.
Highlights
A report of the second known case of bilateral cystoid macular edema in a patient taking risperidone
The retina is vulnerable to medication-induced changes through a variety of mechanisms, Cystoid macular edema (CME) develops when the capillary filtration rate is greater than the rate of fluid removal by glial and retinal pigment epithelium (RPE) cells
Risperidone has effects on a variety of cellular receptors that may result in CME
Summary
A report of the second known case of bilateral cystoid macular edema in a patient taking risperidone. In 2013, the first case of risperidone-related bilateral CME was reported by Manousaridis and Gupta [3]. They described a 65-year-old woman with a past medical history of depression who presented with a 5-week history of bilateral blurred vision.
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