Abstract
Since 1990 the debate about medical screening of workers has been driven largely by four developments that reflect the scientific, political, economic, and legal dimensions of the issue. First, the Human Genome Project, officially started in 1990, is a 15-year, $3-billion program to map and sequence all of the estimated 100 000 human genes. As a result of this initiative, geneticists will be able to assess an ever-widening range of human genetic factors, which will include identifying individuals who are presymptomatic for late-onset single gene disorders, carriers of recessive and X-linked traits, and persons at increased risk for multifactorial disorders. This information will relate primarily to nonoccupationally related disorders, but it still will be of great interest to employers under pressure to reduce the escalating costs of employee health and benefits programs. Second, because our political system has failed to address the inherent conflict raised by a health insurance system
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