Risks of Occupational Respiratory Diseases among U.S. Coal Miners

Abstract

Abstract The excess (exposure-attributable) risks of certain respiratory diseases and outcomes were estimated for U.S. coal miners exposed to respirable coal mine dust for various durations and concentrations, including a 45-year working lifetime at the current 2-mg/m3 standard. Multiple linear and logistic regression models were used to compute predicted prevalence and excess risk of disease, using data and regression results from published epidemiological studies of U.S. coal miners. Disease outcomes evaluated include simple coal workers' pneumoconiosis, progressive massive fibrosis, and clinically significant deficits in lung function, measured as forced expiratory volume in 1 second of < 80% or < 65% of predicted normal values. Point estimates of excess risk of progressive massive fibrosis ranged from 1/1000 to 167/1000 among coal miners exposed to respirable coal mine dust at a mean concentration of 2 mg/m3 for 45 years. This range reflects coal rank and study differences. Point estimates for an exce...