Abstract
AbstractSudden cardiac death (SCD) threatens ischemic cardiomyopathy patients. Antiarrhythmic protection may be provided to these patients with implanted cardiac defibrillators (ICD), after an efficient risk stratification approach. The proposed risk stratifier of an impaired left ventricular ejection fraction has limited sensitivity. Current risk stratification strategies focus on markers that, by identifying the arrhythmic substrate and the severity of the arrhythmia mechanisms present, are also considered to quantify the risk of SCD. Such markers reflect: (1) myocardial substrate lesions and postinfarction fibrosis (LVEF, QRS, LBBB, SAECG, fragmented QRS, CMR, PVBs, NSVT), (2) abnormal repolarization (QT, QTd, T‐wave alternans, QT/RR, QTVI, TWV), (3) impaired autonomic nervous system function (HR, heart rate variability (HRV), HRT, deceleration capacity (DC), BRS, HR recovery after exercise), and (4) inducibility on programmed ventricular stimulation during electrophysiological testing. Ventricular tachyarrhythmias have a strong dynamic component because transient and unpredictable factors can trigger a fatal arrhythmic episode. For this reason, SCD risk stratification is not simple and no ideal marker or a completely successful predictive model is existing. The evolution of technology made possible all the noninvasive markers to be incorporated in the Holter software. Noninvasive risk stratification has been simplified. Innovative Holter technology enforced the doctors, providing them with the tools for primarily screening their patients through the ICD protection process.Answer questions and earn CME: https://wileyhealthlearning.com/Activity2/4469459/Activity.aspx
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.